Author

Hongju Lee

University of PennsylvaniaORCID 0009-0002-3224-0423Unclaimed ORCID profile · follow to get notified of new preprints

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Developmental Biology· 1

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Approach:experimental assay· 1 Organism:mouse· 1

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Hui CheniD· 1 shared Matthew C. GoodiD· 1 shared Wenchao QianiD· 1 shared

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2026-2026 · peak 1/yr

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1 shared paperDevelopmental Biology

Hui ChenORCID

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1 paper

Recent·Most cited

Developmental BiologyThe Journal of Cell BiologyPeer-reviewedJul 14, 2026

Spatially ordered zygotic genome activation fulfills embryo quality control

Wenchao Qian, Hui Chen, Hongju Lee, Matthew C. Good

The paper shows that properly patterned zygotic genome activation (ZGA) is required for normal development and that embryos have a quality control system to detect and respond to mispatterned ZGA.

DOI 10.1083/jcb.202412222

mouseexperimental assay

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