Molecular BiologybioRxivPreprint
On the illusion of auxotrophy: met15Δ yeast cells can grow on inorganic sulfur thanks to the previously uncharacterized homocysteine synthase Yll058w
S. Branden Van Oss, Saurin Bipin Parikh, Nelson Castilho Coelho…·Anne‐Ruxandra Carvunis
The paper shows that yeast cells lacking Met15 can assimilate inorganic sulfur via Yll058w, but require exogenous methionine or hydrogen sulfide chelators to grow, challenging the traditional view of MET15 as essential for sulfur assimilation.
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