Author

Jian Dai

ShanghaiTech UniversityORCID 0000-0002-9435-6213Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

Chunyan Si· 1 shared Feifei XuiD· 1 shared Hui Gao· 1 shared Ian Schacht· 1 shared J. HeiD· 1 shared Kunshan Liu· 1 shared Long‐Cheng LiiD· 1 shared Moorim Kang· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperNeuroscience

Chunyan Si

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintJan 20, 2025

AI-driven discovery of host thioredoxin as a CRISPR enhancer of phage-encoded miniature Cas12 hacker nuclease

Zhipeng Wang, Yujue Wang, Hui Gao…·Quanjiang Ji

This study identifies thioredoxin as a host factor that enhances the DNA cleavage efficiency of a phage-encoded Cas12 nuclease using AI-driven analysis and biochemical validation.

1 citation

E. coliprotein structure

𝕏 PostBluesky

NeurosciencebioRxivPreprintOct 29, 2024

SCAD Delivery Platform: A Novel Approach for Efficient CNS and Extrahepatic Oligonucleotide Therapeutics

Moorim Kang, Wei-Hsiang Lin, Feifei Xu…·Long‐Cheng Li

The paper introduces the SCAD platform for efficient delivery of duplex RNA therapeutics to the CNS and other tissues, showing sustained knockdown and safety in rodent models.

DOI 10.1101/2024.10.29.620792

mouseexperimental assay

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