Author

Ly Vu

University of British ColumbiaORCID 0000-0002-1682-7702Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Developmental Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Glenn EdiniD· 2 shared Luke SavilleiD· 2 shared Quang Anh Hoang· 2 shared Zongmin LiuiD· 2 shared Alexandra SchureriD· 1 shared Aly KarsaniD· 1 shared Amber LouwagieiD· 1 shared Brenda Ma· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Glenn EdinORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

LncRNA-mediated organization of oncogenic chromatin state is a targetable vulnerability in leukemia

Ly Vu, Zhen Jin, Brenda Ma, Karen Chan, Diana Lin, Debajeet Ghosh, Amber Louwagie, Luke Saville, Joanne Liani Chandra, Yilin Liu, Zongmin Liu, Leo Escano, Sandra Spencer Miko, Se Wing Grace Cheng, Priscila Elias Ferreira Stricker, , Pieter R. Cullis

This study identifies PAN3-AS1 as an oncogenic lncRNA in AML, shows its role in chromatin organization, and demonstrates RNA-targeting LNP therapy to reduce leukemia burden.

bioRxiv · Aug 11, 2026 · PreprintCancer Biology

Loss of cell cycle gatekeeping by 1 CNOT3 impairs hematopoietic stem and progenitor cell division and repopulating activity

Katie A. Yuen, Thilelli Taibi, Quang Anh Hoang, Marty Yue, Zongmin Liu, Effat Habibi, Elias Spiliotopoulos, Niveditha Ramkumar, Nick Nation, Glenn Edin, Thuy T. M. Ngo, Ly Vu

This study shows that CNOT3 deletion in HSCs causes anemia, reduced bone marrow cellularity, and impaired hematopoietic reconstitution.

bioRxiv · Oct 23, 2025 · PreprintDevelopmental Biology

Nanopore-based native RNA sequencing of human transcriptomes reveals the complexity of mRNA modifications and crosstalk between RNA regulatory features

Yerin Kim, Kieran O’Neill, Jean‐Michel Garant, Luke Saville, Simon Haile, Maryam Ghashghaei, Yongjin Park, Steven J.M. Jones, Ly Vu

This study uses nanopore sequencing to analyze RNA modifications and their correlations with other RNA features in human cells, revealing negative associations and pathway-specific responses.

bioRxiv · Jul 11, 2024 · PreprintGenomics