Author

Louise Tzung-Harn Hsieh

Institute of Molecular Biology, Academia SinicaORCID 0000-0002-9499-889XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:virus· 2

Frequent Co-Authors

Der‐Lii M. TzouiD· 2 shared Hsiao-Jung ChiuiD· 2 shared Kathleen Joyce CarilloiD· 2 shared Wen ChangiD· 2 shared Chang Sheng‐Huei LiniD· 1 shared Yuan‐Chao LouiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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2 shared papersMicrobiology

Der‐Lii M. TzouORCID

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2 papers

Recent·Most cited

Structure and functional analyses of vaccinia virus J5 protein reveal distinct determinants for entry-fusion complex assembly and activation

Hsiao-Jung Chiu, Kathleen Joyce Carillo, Louise Tzung-Harn Hsieh, Yuan‐Chao Lou, Chang Sheng‐Huei Lin, Der‐Lii M. Tzou, Wen Chang

This study determines the structure of vaccinia virus J5 protein and identifies key regions for EFC assembly and membrane fusion.

Journal of Virology · Jul 6, 2026Peer-reviewedMicrobiology

Structure and functional analyses of Vaccinia virus entry- fusion complex component J5 protein

Hsiao-Jung Chiu, Louise Tzung-Harn Hsieh, Kathleen Joyce Carillo, Der‐Lii M. Tzou, Wen Chang

The paper determines the NMR structure of J5 protein and identifies functional residues critical for EFC integrity and membrane fusion in Vaccinia virus entry.

bioRxiv · Nov 13, 2025 · PreprintMicrobiology