Kathleen Joyce Carillo

This study identifies the flexible N-terminal domain of Sorcin as a critical regulator that enhances Ca2+ responsiveness by stabilizing its active conformation through dynamic contacts.

This study benchmarks deep learning models' ability to predict mutation-induced fold switching in proteins using an NMR-characterized dataset of fold-switching mutants.

This study uses long-timescale molecular dynamics simulations to show that Ca2+ binding shifts pre-existing active states in Sorcin rather than inducing activation de novo.

This study determines the structure of vaccinia virus J5 protein and identifies key regions for EFC assembly and membrane fusion.

The paper determines the NMR structure of J5 protein and identifies functional residues critical for EFC integrity and membrane fusion in Vaccinia virus entry.

The paper identifies cold-sensitive protein conformational changes across the proteome using mass spectrometry in E. coli.

This study investigates calcium-induced Sorcin aggregation using stopped-flow light scattering, finding that aggregation is reversible, cooperative, and concentration-dependent.

This study reveals a pH-induced conformational switching mechanism in Betanodavirus protrusions that governs infectivity through dynamic structural changes.