Author

Joseph Francis

Louisiana State UniversityORCID 0000-0002-9502-4579Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:mouse· 3 Assay:ATAC-seq· 2 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:CUT&Tag· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Jiangwen Sun· 3 shared Leshan Wang· 3 shared Qianglin LiuiD· 3 shared Xing FuiD· 3 shared YUXIA LIiD· 3 shared Xujia ZhangiD· 2 shared Adam X. Bao· 1 shared Boyu Li· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersGenomics

Jiangwen Sun

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Multiomics reveals epigenetic control of fibroblast activity after myocardial infarction and a key role for RUNX transcription factors

YUXIA LI, Xujia Zhang, Kishan Ghimire, Nishan Khatri, Leshan Wang, Qianglin Liu, Mohammad Shiri, Rayyan Shakoori, Sachin Upadhayaya, Boyu Li, Joseph Francis, Constantine A. Simintiras, Rui Li, Jiangwen Sun, Xing Fu

This study uses multi-omics approaches to show that Runx1 regulates cardiac fibroblast activity and differentiation after myocardial infarction, with its deletion improving cardiac repair.

bioRxiv · Jan 13, 2026 · PreprintGenomics

Loss of Acta2 in cardiac fibroblasts does not prevent myofibroblast differentiation or affect cardiac repair after myocardial infarction

Yuxia Li, Chaoyang Li, Qianglin Liu, Leshan Wang, Adam X. Bao, Jangwook P. Jung, Sanjeev Dodlapati, Jiangwen Sun, Peidong Gao, Xujia Zhang, Joseph Francis, Jeffery D. Molkentin, Xing Fu

Journal of Molecular and Cellular Cardiology · Aug 22, 2022Peer-reviewedMolecular Biology

The landscape of accessible chromatin in quiescent and post-myocardial infarction cardiac fibroblasts

Chaoyang Li, Jiangwen Sun, Qianglin Liu, Sanjeeva Dodlapati, Hao Ming, Leshan Wang, Yuxia Li, Rui Li, Zongliang Jiang, Joseph Francis, Xing Fu

This study examines chromatin accessibility and gene expression in cardiac fibroblasts before and after myocardial infarction using ATAC-seq and RNA-seq, revealing correlations between promoter accessibility and gene expression, and identifying potential transcription factors involved in differential gene expression.

bioRxiv · Mar 3, 2021 · PreprintGenomics