Author

S. Chul Kwon

University of Hong KongORCID 0000-0002-9519-5132Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Biochemistry· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Assay:CRISPR screen· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:proteomics· 1

Frequent Co-Authors

Abigail J Dennis· 1 shared Adriana LoriiD· 1 shared Alisa M. GoldsteiniD· 1 shared Amy HutchinsoniD· 1 shared Belynda D. HicksiD· 1 shared Bobo Wing-Yee MokiD· 1 shared Chi Fai Lau· 1 shared Douglas R. StewartiD· 1 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperGenetic & Genomic Medicine

Abigail J Dennis

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintJun 2, 2026

Disruption of CTCF binding by germline non-coding variants in CDKN2B suppress CDKN2A expression and predispose to melanoma

Jessica L. Scales, Jayne A. Barbour, Alisa M. Goldstein…·Xiaohong R Yang

The paper identifies non-coding variants in CDKN2B that disrupt CTCF binding, reduce CDKN2A expression, and increase melanoma risk in families.

DOI 10.64898/2026.06.01.26352322

humanwhole-exome sequencing

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Molecular BiologybioRxivPreprintNov 17, 2025

High-resolution RNA knockdown profiles of small RNA and Cas13 systems

Jonathan Kong, Summerloretta S. K. Leung, Guojia Wu…·S. Chul Kwon

This study compares RNA knockdown profiles of small RNA and Cas13 systems to identify structural rules governing target-site selection.

DOI 10.1101/2025.11.17.688664

humanCRISPR screen

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BiochemistryEMBO ReportsPeer-reviewedFeb 26, 2025

Cytosolic CRISPR RNA for RNA-targeting CRISPR-Cas systems

Ezra C.K. Cheng, Jodie Lam, S. Chul Kwon

This study shows that U1-driven CRISPR RNAs enhance the efficiency of RNA-targeting CRISPR-Cas13 systems for knockdown and editing without modifying Cas13 proteins.

6 citations

CRISPR screenproteomics

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Molecular BiologybioRxivPreprintMay 13, 2020

ERH as a component of the Microprocessor facilitates the maturation of suboptimal microRNAs

S. Chul Kwon, Harim Jang, Ji-Hye Yang…·V. Narry Kim

This study identifies ERH as a new component of the Microprocessor complex that enhances processing of suboptimal pri-miRNAs in polycistronic clusters.

DOI 10.1101/2020.05.13.093278

experimental assay

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