Adriana Lori

Disruption of CTCF binding by germline non-coding variants in CDKN2B suppress CDKN2A expression and predispose to melanoma

The paper identifies non-coding variants in CDKN2B that disrupt CTCF binding, reduce CDKN2A expression, and increase melanoma risk in families.

Genetic regulation of microRNAs in the older adult brain and their contribution to neuropsychiatric conditions

The paper identifies miR-QTLs in older adult brains and links four miRNAs to multiple neuropsychiatric and neurodegenerative diseases through integration with GWAS results.

Genome-wide association study meta-analysis of suicide attempt identifies twelve genome-wide significant loci and implicates genetic risks for specific health factors

This paper conducts a multi-ancestry GWAS meta-analysis of suicide attempt, identifying 12 genome-wide significant loci and finding shared genetic risks with ADHD, smoking, and risk tolerance.

Dissecting the shared genetic architecture of suicide attempt, psychiatric disorders and known risk factors

This study identifies genetic loci associated with suicide attempts and shows shared genetic architecture with psychiatric disorders and non-psychiatric risk factors.

Brain microRNAs associated with late-life depressive symptoms are also associated with cognitive trajectory and dementia

The paper identifies brain microRNAs linked to late-life depressive symptoms and shows their association with cognitive decline and dementia risk.

Methylomic profiles reveal sex-specific shifts in leukocyte composition associated with post-traumatic stress disorder

The paper identifies sex-specific changes in monocyte proportions in males with PTSD using methylomic data, showing no such changes in females.

Epigenome-wide meta-analysis of PTSD across 10 military and civilian cohorts identifies novel methylation loci

This study identifies ten novel methylation loci associated with PTSD through a meta-analysis of 1,896 cases and controls across ten cohorts, highlighting the AHRR locus and its link to kynurenine levels.

Analysis of Genetically Regulated Gene Expression identifies a trauma type specific PTSD gene, SNRNP35

The paper identifies SNRNP35 as a trauma type-specific PTSD gene through analysis of genetically regulated gene expression in PTSD cases and controls.

Largest genome-wide association study for PTSD identifies genetic risk loci in European and African ancestries and implicates novel biological pathways

This study conducts the largest GWAS for PTSD, identifying 6 genome-wide significant loci in European and African ancestries and highlighting novel biological pathways.

Genome wide association study of hippocampal subfield volume in PTSD cases and trauma-exposed controls

The paper conducts a GWAS of hippocampal subfield volumes in PTSD cases and trauma-exposed controls, identifying genetic associations and gene-environment interactions.