Author

Adéla Šimková

Charles UniversityORCID 0000-0002-9526-4708Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Filip WichterleiD· 1 shared Jan KonvalinkaiD· 1 shared Jana StaňurováiD· 1 shared Kateřina ČermákováiD· 1 shared Pavel ŠáchaiD· 1 shared Petr BušekiD· 1 shared Robin KryštůfekiD· 1 shared Zdislava Vaníčková· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperBiochemistry

Filip WichterleORCID

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1 paper

Recent·Most cited

Sensitive quantification of fibroblast activation protein and high-throughput screening for inhibition by FDA-approved compounds

Kateřina Čermáková, Adéla Šimková, Filip Wichterle, Robin Kryštůfek, Jana Staňurová, Zdislava Vaníčková, Petr Bušek, Jan Konvalinka, Pavel Šácha

The paper presents a qPCR-based method for high-throughput screening of FDA-approved compounds as FAP inhibitors and demonstrates its application in quantifying FAP in human plasma.

European Journal of Medicinal Chemistry · Oct 9, 2024Peer-reviewedBiochemistry