Jan Konvalinka

The paper shows that peptides made from non-standard amino acids can form protein-like secondary structures, expanding the known sequence-structure space beyond Earth's 20 amino acids.

This study shows random 25-mer peptides with a prebiotically plausible amino acid alphabet can self-assemble into thermostable beta-rich nanostructures.

The paper develops a non-radioactive screening assay for insulin receptor ligands that is faster and more sensitive than existing radioligand assays.

The paper presents a qPCR-based method for high-throughput screening of FDA-approved compounds as FAP inhibitors and demonstrates its application in quantifying FAP in human plasma.

This paper develops polymer-tethered fluorescent probes for tumor-associated protease imaging, showing improved signal and tumor-to-background ratios compared to small molecule probes.

This study shows that yeast proteases Ddi1 and Wss1 are both involved in the DNA replication stress response, with Ddi1's helical domain playing a key role.