Author

Dennis G. Moledina

Yale UniversityORCID 0000-0002-9537-9038Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Organism:human· 2 Assay:spatial transcriptomics· 2 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Alexandra–Chloé VillaniiD· 1 shared Api ChewcharatiD· 1 shared Astrid WeinsiD· 1 shared Avi Z. RosenbergiD· 1 shared Ce GaoiD· 1 shared Chirag R. ParikhiD· 1 shared David E. LeafiD· 1 shared Deepak A. RaoiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperImmunology

Alexandra–Chloé VillaniORCID

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2 papers

Recent·Most cited

ImmunologyNature CommunicationsPeer-reviewedAug 27, 2026

Spatial analysis reveals the cellular microenvironments and mechanisms of inflammation and kidney injury in acute interstitial nephritis

Megan Leila Baker, Vijayakumar R. Kakade, Tifanny Budiman…·Lloyd G. Cantley

The paper identifies the CXCL9-CXCR3 axis and NAMPT as key drivers of inflammation and kidney injury in acute interstitial nephritis using spatial transcriptomics and imaging.

DOI 10.1038/s41467-026-77210-y

humanspatial transcriptomics

ImmunologybioRxivPreprintOct 31, 2025

Spatial Transcriptomics Identify T Cell-Driven Mechanisms of Kidney Damage in Immune Checkpoint Inhibitor-Associated Acute Interstitial Nephritis

Qian Qin, Lennard Ostendorf, Sophia L. Wells…·Shruti Gupta

This study uses spatial transcriptomics to identify CD8+ T cell-driven mechanisms of kidney damage in ICI-AIN, showing increased IFN-γ signaling and proinflammatory myeloid cell activation.

3 citations

humanspatial transcriptomics