Author

Jayne E Wiarda

Agricultural Research ServiceORCID 0000-0002-9538-2720Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Assay:scRNA-seq· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:non-human primate· 1 Organism:plant (other)· 1

Frequent Co-Authors

Alexandra BuckleyiD· 2 shared Bailey L. ArrudaiD· 2 shared Eraldo Lourenso ZanellaiD· 2 shared Hanjun KimiD· 2 shared Jianqiang ZhangiD· 2 shared Samantha J. HauiD· 2 shared Christopher Keith TuggleiD· 1 shared Crystal Lynn LovingiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersImmunology

Alexandra BuckleyORCID

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3 papers

Recent·Most cited

Porcine epidemic diarrhea virus infection promotes Peyer's patch immune induction and epithelial defense via single-cell transcriptional reprogramming

Jayne E Wiarda, Bailey L. Arruda, Eraldo Lourenso Zanella, Hanjun Kim, Samantha J. Hau, Jianqiang Zhang, Alexandra Buckley

This study uses scRNA-seq to analyze how PEDV infection alters transcriptional responses in intestinal epithelial and immune cells, identifying a conserved antiviral gene signature in enterocytes.

Microbiology Spectrum · Sep 2, 2026Peer-reviewedImmunology

A single-cell immune atlas of primary and secondary lymphoid organs in pigs

Jayne E Wiarda, Muskan Kapoor, Sathesh Kumar Sivasankaran, Kristen A. Byrne, Crystal Lynn Loving, Christopher Keith Tuggle

This study creates a single-cell immune atlas of pig lymphoid organs using scRNA-seq, identifying conserved immune cell populations between pigs and humans.

Frontiers in Immunology · Mar 4, 2026Peer-reviewedImmunology

United States PRRSV 1-4-4 L1C.5 isolate demonstrates similar pathogenicity to a historic Chinese highly pathogenic PRRSV

Jayne E Wiarda, Bailey L. Arruda, Tavis K. Anderson, Sarah J. Anderson, Hanjun Kim, Tyron Chang, Lauren Tidgren Hanson, Eraldo Lourenso Zanella, Samantha J. Hau, Meghan Wymore Brand, Jianqiang Zhang, Alexandra Buckley

This study compares the pathogenicity of PRRSV 1-4-4 L1C.5 to historical Chinese HP-PRRSV JXwn06 and US strain MN184 in weaned pigs, finding L1C.5 and JXwn06 cause more severe disease than MN184.

Virology · Nov 26, 2025Peer-reviewedMicrobiology