Author

Victor M. Karpyak

Mayo ClinicORCID 0000-0002-9552-6130Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1

Frequent Co-Authors

Brandon J. CoombesiD· 2 shared Joanna M. BiernackaiD· 2 shared Richard M. WeinshilboumiD· 2 shared Abedalrahman Jomaa· 1 shared Ada Man‐Choi HoiD· 1 shared Anthony J. BatzleriD· 1 shared Ateka Saleh· 1 shared August J. JohniD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersGenomics

Brandon J. CoombesORCID

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2 papers

Recent·Most cited

Alcohol Use Disorder Associated Gene FNDC4 Alters Glutamatergic and GABAergic Neurogenesis

Xiujuan Zhu, August J. John, Li Wang, Sooan Kim, Enci Ding, Ateka Saleh, Irene Marín-Goñi, Abedalrahman Jomaa, Huanyao Gao, Ching Man Wai, Irene Moon, Brandon J. Coombes, Tony M. Kerr, Nobuyoshi Suto, Liewei Wang, , Duan Liu

The paper identifies FNDC4 as a gene associated with alcohol use disorder through GWAS and shows its role in regulating neurogenesis via alternative splicing and CRISPR/Cas9 experiments.

bioRxiv · May 15, 2025 · PreprintGenomics

Genetic Contributions to Alcohol Use Disorder Treatment Outcomes: A Genome-wide Pharmacogenomics Study

Joanna M. Biernacka, Brandon J. Coombes, Anthony J. Batzler, Ada Man‐Choi Ho, Jennifer R. Geske, Josef Frank, Colin A. Hodgkinson, Michelle K. Skime, Colin L. Colby, Lea Zillich, Sofia Pozsonyiova, Ming‐Fen Ho, Falk Kiefer, Marcella Rietschel, Richard M. Weinshilboum, , Victor M. Karpyak

This study identifies genetic variants associated with AUD treatment outcomes using pharmacogenomic analyses of naltrexone and acamprosate responses.

Neuropsychopharmacology · Jul 23, 2021Peer-reviewedGenetic & Genomic Medicine