Xiaoyu Chen

Mapping brain-wide excitatory projectome of primate prefrontal cortex at submicron resolution: relevance to diffusion tractography

The paper maps excitatory axonal projections from the macaque ventrolateral prefrontal cortex to the whole brain at submicron resolution, revealing discrepancies with diffusion tractography.

MECP2 duplication causes aberrant GABA pathways, circuits and behaviors in transgenic monkeys: neural mappings to patients with autism

The paper identifies shared circuit-level abnormalities between MECP2 transgenic monkeys and a subgroup of human autism patients, highlighting the need for a multimodal approach to study genetic effects in a primate model.

Resting-state connectivity predicts patient-specific effects of deep brain stimulation for Parkinson’s disease

This paper uses functional brain connectomes to predict optimal deep brain stimulation targets for Parkinson’s disease patients, finding that globus pallidus and subthalamic nucleus are top choices for a significant proportion of patients.