Jason Yeung

NEMO recruitment at single cytokine-receptor complexes shows quantized dynamics independent of ligand affinity

The paper investigates how IL-1 receptor signaling dynamics are quantized and independent of ligand affinity using experimental and modeling approaches.

Mechanistic Insights into Dengue Virus Inhibition by a Clinical Trial Compound NITD-688

This study identifies how NITD-688 inhibits dengue virus by binding NS4B and disrupting its interaction with NS3, reducing viral replication.

Same-Slide Spatial Multi-Omics Integration Reveals Tumor Virus-Linked Spatial Reorganization of the Tumor Microenvironment

This paper introduces IN-DEPTH and SGCC for spatial multi-omics analysis, revealing EBV-related immunomodulatory differences in DLBCL.

Cross-domain information fusion for enhanced cell population delineation in single-cell spatial-omics data

This paper introduces CellSNAP, a self-supervised method that integrates spatial, transcriptomic, and proteomic data to improve cell population delineation in spatial-omics datasets.

ViReMa: A Virus Recombination Mapper of Next-Generation Sequencing data characterizes diverse recombinant viral nucleic acids

ViReMa is updated to detect recombination events in long-read sequencing data and reports various recombinant species in different viral contexts.

ViReMaShiny: An Interactive Application for Analysis of Viral Recombination Data

ViReMaShiny provides an interactive web tool for visualizing and analyzing viral recombination data in BED format, improving accessibility and downstream analysis.