Daniel N. Conrad

The paper introduces MULTI-ATAC, a method to reduce batch effects in scATAC-seq by pooling samples before transposition, enabling scalable and batch-free experiments.

The paper identifies age-dependent selection forces that drive mtDNA mutation accumulation in liver cells, leading to functional decline.

deMULTIplex2 improves sample demultiplexing in scRNA-seq by accurately associating cell tags with sample tags, outperforming existing methods on large, noisy, and imbalanced datasets.

This paper introduces ATAC-DoubletDetector, a read count-based method to detect multiplets in snATAC-seq data and annotate their cellular origins, achieving 85% accuracy in annotation.

The paper introduces MULTI-seq, a method for scalable sample multiplexing in scRNA-seq, enabling analysis of multiple tissues and perturbation experiments while improving data quality.