Juliane Winkler

The paper profiles myeloid cells in breast cancer primary tumors and metastases to show how tumor heterogeneity drives shifts in myeloid cell phenotypes from anti- to pro-metastatic.

LazySlide provides an open-source Python package for whole-slide image analysis and multimodal integration, enabling efficient histopathology workflows with minimal setup.

The paper shows that gap junctions between breast cancer cells and adipocytes transfer cAMP, activating lipolysis in the tumor microenvironment to support tumor growth.

This study uses Perturb-seq to functionally interrogate SARS-CoV-2 host factors in human lung epithelial cells, identifying key factors that influence infection and host response.

Nearly 500,000 cells from 24 human tissues, many from one donor, characterize over 400 cell types and enable within-donor study of T-cell clones, B-cell mutation rates and splicing.

The paper introduces MULTI-seq, a method for scalable sample multiplexing in scRNA-seq, enabling analysis of multiple tissues and perturbation experiments while improving data quality.