Author

Lisa A. Purcell

Regeneron (United States)ORCID 0000-0002-9565-2030Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:proteomics· 1 Research Focus:variant calling· 1 Organism:virus· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Adrienne P. Gilkes· 1 shared Aishwarya MandavaiD· 1 shared Alessandro SetteiD· 1 shared Andrey Kochergin· 1 shared Bali PulendraniD· 1 shared Bin HuiD· 1 shared Bjoern PetersiD· 1 shared Chien‐Chi LoiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperSystems Biology

Adrienne P. Gilkes

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Towards increased accuracy and reproducibility in SARS-CoV-2 next generation sequence analysis for public health surveillance

Ryan P. Connor, Migun Shakya, David A. Yarmosh, Wolfgang Maier, Ross Martin, Rebecca Bradford, James Rodney Brister, Patrick Chain, Courtney A. Copeland, Julia di Iulio, Bin Hu, Philip J. Ebert, Jonathan Gunti, Yumi Jin, Kenneth Katz, , Kim D. Pruitt

This study evaluates the impact of sequencing technologies and bioinformatic protocols on SARS-CoV-2 variant calling and introduces standardized parameters to improve pipeline consistency.

Viruses · Mar 11, 2024Peer-reviewedBioinformatics

A system-view of B. pertussis booster vaccine responses in adults primed with whole-cell vs. acellular vaccine in infancy

Ricardo da Silva Antunes, Mikhail Pomaznoy, Ferran Soldevila, Mariana Babor, Jason Bennett, Yuan Tian, Natalie Khalil, Qian Yu, Aishwarya Mandava, Richard H. Scheuermann, Mario Cortese, Bali Pulendran, Christopher D. Petro, Adrienne P. Gilkes, Lisa A. Purcell, , Bjoern Peters

The paper compares immune responses to a Tdap booster in adults primed with acellular (aP) or whole-cell (wP) pertussis vaccines, identifying divergent gene expression and antibody subtype patterns in aP-primed individuals.

JCI Insight · Mar 9, 2021Peer-reviewedSystems Biology