Phil Palmer

Safety First: Input Screening for Protein Design Tools

The paper introduces a screening method for protein design tools that evaluates functional and structural features to identify potentially harmful targets, showing high accuracy and distinguishing between benign and damaging mutations.

Digitally immune optimised haemagglutinin with nanocage plug-and-display elicits broadly neutralising pan-H5 influenza subtype vaccine responses

This paper develops a vaccine candidate using DIOSvax-H5inter nanocages that elicits cross-clade neutralising antibodies and T cell responses against diverse H5 influenza strains.

Covering All Bases: A Computational Method to Design Broad-spectrum T-cell-inducing Vaccines Applied to Betacoronaviruses

This paper introduces Spectravax, a computational method to design broad-spectrum T-cell-inducing vaccines, and demonstrates its effectiveness against Betacoronaviruses.