Simultaneous broad protection against Ebola Sudan, Marburg and Lassa viruses conferred by a DNA primed MVA-vectored multivalent vaccine
Darwyn Kobasa, Martina Pfranger, Nina Krause…·Jonathan Luke Heeney
Author
University of CambridgeORCID 0000-0003-2702-1621Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
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Darwyn Kobasa, Martina Pfranger, Nina Krause…·Jonathan Luke Heeney
Joanna Vieira O'Neill, Joash Tan, Ed Long…·George Carnell
The paper reports high seroprevalence of SARS-CoV-2 in British deer, indicating potential reservoir capability and zoonotic risks from human-deer interactions.
Joanne Marie M. Del Rosario, Pauline M. van Diemen, Simon D. W. Frost…·Jonathan Luke Heeney
This paper demonstrates the immunogenicity and efficacy of a computationally designed DNA vaccine against H1N1 influenza in swine and mice, showing broad neutralizing antibody responses and reduced viral shedding.
Chloe Qingzhou Huang, Rory A. Hills, George Carnell…·Jonathan Luke Heeney
This paper develops a vaccine candidate using DIOSvax-H5inter nanocages that elicits cross-clade neutralising antibodies and T cell responses against diverse H5 influenza strains.
Phil Palmer, Sofiya Fedosyuk, Srivatsan Parthasarathy…·Sneha Vishwanath
This paper introduces Spectravax, a computational method to design broad-spectrum T-cell-inducing vaccines, and demonstrates its effectiveness against Betacoronaviruses.
Anise N. Happi, Olusola Akinola Ogunsanya, Judith Uche Oguzie…·Christian Tientcha Happi
The paper reports the first genomic characterization of RHDV2 in sub-Saharan Africa using metagenomic sequencing and identifies genetic diversity in GI.2 strains.