Author

Steven De Vleeschouwer

Universitair Ziekenhuis LeuvenORCID 0000-0002-9576-9917Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:spatial transcriptomics· 3 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

Ann HoebeniD· 2 shared Carmen Bravo González‐BlasiD· 2 shared Frederik De SmetiD· 2 shared Jonathan Sai‐Hong ChuiiD· 2 shared Martinus P. G. BroeniD· 2 shared Raf SciotiD· 2 shared Aaron Ziani ZeryouhiD· 1 shared An CoosemansiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersMolecular Biology

Ann HoebenORCID

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3 papers

Recent·Most cited

Macrophage-instructed GSDME couples glioblastoma cell-state plasticity with inflammatory cell death

Yihan Yang, Jonathan Sai‐Hong Chui, Ellen Vervoort, Julie Van Nieuwenhuyze, Shikang Zhao, Carmen Bravo González‐Blas, Kinga Anna Nowak, Sanket More, Kathryn Jacobs, Aaron Ziani Zeryouh, Nikolina Dubroja, Raf Sciot, An Coosemans, Massimiliano Mazzone, Frederik De Smet, , Patrizia Agostinis

This paper identifies GSDME-FL as a macrophage-instructed regulator of glioblastoma cell-state plasticity and inflammatory cell death, showing its role in tumor progression and immune response.

bioRxiv · Jul 23, 2026 · PreprintCancer Biology

Spatial Single Cell Lipid-Transcriptomic Coupling Reveals Metabolic Niches in Glioblastoma

Tim Hendriks, Gert B. Eijkel, Martinus P. G. Broen, Ann Hoeben, Steven De Vleeschouwer, Ron M. A. Heeren, Eva Cuypers

This study integrates spatial transcriptomics and MALDI-MSI to reveal spatial lipid-gene coupling in glioblastoma, showing distinct metabolic niches in tumor-core and invasive regions.

bioRxiv · Jul 14, 2026 · PreprintMolecular Biology

Longitudinal tumor ecosystem mapping defines glioblastoma treatment trajectories

Maxime Vanmechelen, Pouya Nazari, Jan C. Beckervordersandforth, Chiara Caprioli, Daphne J. G. Leunissen, Basiel Cole, Carmen Bravo González‐Blas, Brecht Decraene, Yanti De Visser, G Shankar, Maikel Verduin, daniele Pantano, Sien Bevers, Tom Moors, Shanna Zielinski, , Frederik De Smet

This study maps glioblastoma tumor ecosystems over time using spatial single-cell profiling to identify prognostic subgroups and treatment responses.

bioRxiv · Mar 7, 2026 · PreprintCancer Biology