Author

Nikolina Dubroja

KU Leuven

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 2 Approach:deep learning· 2 Research Focus:differential expression· 2 Assay:spatial transcriptomics· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1

Frequent Co-Authors

Frederik De SmetiD· 3 shared Kinga Anna NowakiD· 2 shared Aaron Ziani ZeryouhiD· 1 shared Alexandre ArnouldiD· 1 shared An CoosemansiD· 1 shared Asier AntoranziD· 1 shared Bart De MooriD· 1 shared Bernhard RobliD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersCancer Biology

Frederik De SmetORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Macrophage-instructed GSDME couples glioblastoma cell-state plasticity with inflammatory cell death

Yihan Yang, Jonathan Sai‐Hong Chui, Ellen Vervoort, Julie Van Nieuwenhuyze, Shikang Zhao, Carmen Bravo González‐Blas, Kinga Anna Nowak, Sanket More, Kathryn Jacobs, Aaron Ziani Zeryouh, Nikolina Dubroja, Raf Sciot, An Coosemans, Massimiliano Mazzone, Frederik De Smet, , Patrizia Agostinis

This paper identifies GSDME-FL as a macrophage-instructed regulator of glioblastoma cell-state plasticity and inflammatory cell death, showing its role in tumor progression and immune response.

bioRxiv · Jul 23, 2026 · PreprintCancer Biology

Microglial lipid signaling drives glioblastoma invasion and represents a therapeutic vulnerability

Carla Pallarés-Moratalla, Mélanie Guyot, Krish Skandha Gopalan, Bernhard Robl, Jakub Idkowiak, Jonas Dehairs, Nina Ravoet, Kinga Anna Nowak, Nikolina Dubroja, Linqian Weng, Vasileios Konstantakos, Xander Spotbeen, Sarah‐Maria Fendt, Stein Aerts, Frederik De Smet, , Gabriele Bergers

This study identifies a lipid-mediated signaling pathway driven by microglia that promotes glioblastoma invasion and shows that targeting this pathway can suppress tumor invasion.

bioRxiv · Apr 28, 2026 · PreprintCancer Biology

QUAL-IF-AI: Quality Control of Immunofluorescence Images using Artificial Intelligence

Madhavi Dipak Andhari, Giulia Rinaldi, Pouya Nazari, Gautam Shankar, Nikolina Dubroja, Johanna Vets, Tessa Ostyn, Maxime Vanmechelen, Brecht Decraene, Alexandre Arnould, Willem Mestdagh, Bart De Moor, Frederik De Smet, Francesca Maria Bosisio, Asier Antoranz

QUAL-IF-AI is a deep learning tool that detects and manages artifacts in multiplex immunofluorescence images, achieving high accuracy and IoU across common artifact types.

bioRxiv · Jan 26, 2024 · PreprintBioinformatics