An Coosemans

This paper identifies GSDME-FL as a macrophage-instructed regulator of glioblastoma cell-state plasticity and inflammatory cell death, showing its role in tumor progression and immune response.

MetDecode uses methylation patterns to estimate tumor proportion and identify tissue origin in cell-free DNA samples from cancer patients.

This paper introduces an optimal transport-based domain adaptation method to correct technical biases in cfDNA sequencing data, improving cancer detection and enabling cohort integration.

The paper develops a method to detect and type cancer using cfDNA sequencing data, achieving 81.62% accuracy in distinguishing malignant from control samples.

This study evaluates the feasibility and survival impact of applying the clinical standard of care to glioblastoma mouse models, showing improved outcomes when treatments are combined.