Author

Fatma Cankara

Koç UniversityORCID 0000-0002-9595-3722Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Assay:protein structure· 3 Research Focus:benchmarking· 2 Research Focus:database / resource· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:protein sequence· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Attila GürsoyiD· 3 shared Özlem KeskiniD· 3 shared Ahenk Zeynep SayiniD· 2 shared Simge SenyuziD· 2 shared Nurcan TunçbağiD· 1 shared Tunca DoğaniD· 1 shared Zeynep AbaliiD· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 12 mutual co-author links

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3 shared papersBioinformatics

Attila GürsoyORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

DiPPI: A curated dataset for drug-like molecules in protein-protein interfaces

Fatma Cankara, Simge Senyuz, Ahenk Zeynep Sayin, Attila Gürsoy, Özlem Keskin

The paper introduces DiPPI, a curated dataset of drug-like molecules in protein-protein interfaces, along with a website for drug repurposing studies, containing 55,135 interface-drug interactions.

Journal of Chemical Information and Modeling · Jun 22, 2024Peer-reviewedBioinformatics

Comparative Analysis of Structural Alignment Algorithms for Protein-Protein Interfaces in Template-Based Docking Studies

Fatma Cankara, Nurcan Tunçbağ, Attila Gürsoy, Özlem Keskin

This study compares four structural alignment algorithms for protein-protein interfaces in template-based docking, finding that TM-align performs well despite not being designed for sequence-order independent alignment.

bioRxiv · Apr 3, 2024 · PreprintBioinformatics

Conformational diversity and protein-protein interfaces in drug repurposing in Ras signaling pathway

Ahenk Zeynep Sayin, Zeynep Abali, Simge Senyuz, Fatma Cankara, Attila Gürsoy, Özlem Keskin

The paper identifies FDA-approved drugs that may bind to structurally similar protein-protein interfaces in the Ras/Raf/MEK/ERK pathway, increasing structural coverage from 21% to 92% using PRISM.

bioRxiv · Aug 3, 2023 · PreprintBioinformatics

ASCARIS: Positional Feature Annotation and Protein Structure-Based Representation of Single Amino Acid Variations

Fatma Cankara, Tunca Doğan

ASCARIS provides a comprehensive representation of single amino acid variations by integrating positional and structural features, showing competitive performance in variant effect prediction.

Computational and Structural Biotechnology Journal · Jan 1, 2023Peer-reviewedBioinformatics