Author

Bradley A. Spicer

Monash UniversityORCID 0000-0002-9595-918XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Assay:protein structure· 1

Frequent Co-Authors

Ashleigh KroppiD· 1 shared Christopher J. LuptoniD· 1 shared Chunxiao WangiD· 1 shared Daniel FoxiD· 1 shared Gavin J. KnottiD· 1 shared Hariprasad VenugopaliD· 1 shared Imogen SamuelsiD· 1 shared Kazem AsadollahiiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBiochemistry

Ashleigh KroppORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Inhibiting heme-piracy by pathogenic Escherichia coli using de novo-designed proteins

Daniel Fox, Kazem Asadollahi, Imogen Samuels, Bradley A. Spicer, Ashleigh Kropp, Christopher J. Lupton, Kevin Lim, Chunxiao Wang, Hariprasad Venugopal, Marija Dramićanin, Gavin J. Knott, Rhys Grinter

This study designs de novo proteins to inhibit E. coli's heme extraction from hemoglobin, demonstrating their effectiveness at low nanomolar concentrations.

Nature Communications · Jul 9, 2025Peer-reviewedBiochemistry