Author

Imogen Samuels

The University of MelbourneORCID 0009-0009-8861-6590Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Assay:electronic health records· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Ashleigh KroppiD· 2 shared Chunxiao WangiD· 2 shared Gavin J. KnottiD· 2 shared Hariprasad VenugopaliD· 2 shared Rhys GrinteriD· 2 shared Bradley A. SpiceriD· 1 shared Christopher A. McDevittiD· 1 shared Christopher J. LuptoniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersMicrobiology

Ashleigh KroppORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintSep 18, 2025

A Protein Antibiotic Inhibits the BAM Complex to Kill Without Cell Entry

Fabian Munder, Matthew D. Johnson, Imogen Samuels…·Rhys Grinter

This study shows that L-type pyocins inhibit the BAM complex at the cell surface to kill Pseudomonas aeruginosa without entering the cell.

DOI 10.1101/2025.09.18.677229

bacteria (other)electronic health records

𝕏 PostBluesky

BiochemistryNature CommunicationsPeer-reviewedJul 9, 2025

Inhibiting heme-piracy by pathogenic Escherichia coli using de novo-designed proteins

Daniel Fox, Kazem Asadollahi, Imogen Samuels…·Rhys Grinter

This study designs de novo proteins to inhibit E. coli's heme extraction from hemoglobin, demonstrating their effectiveness at low nanomolar concentrations.

18 citationstop 1%

E. coliprotein structure

𝕏 PostBluesky