GenomicsbioRxivPreprint
The Hippo kinase LATS1 controls CTCF chromatin occupancy and the hormonal response of three-dimensionally grown breast cancer cells
Julieta Ramírez-Cuéllar, Roberto Ferrari, Rosario T. Sanz…·Guillermo Pablo Vicent
This study shows that 3D culture of breast cancer cells alters chromatin structure and gene expression, with LATS1 kinase playing a key role in CTCF displacement and hormonal response.
DOI 10.1101/2023.11.20.566232