GeneticsbioRxivPreprint
Deficiency in Lyst function leads to accumulation of secreted proteases and predisposition to mechanic stress-induced retinal detachment
Xiaojie Ji, Lihong Zhao, Ankita Umapathy…·Patsy M. Nishina
This study shows that Lyst deficiency in mice leads to retinal detachment by causing phagosome accumulation and increased proteases in retinal pigment epithelial cells.
DOI 10.1101/2021.07.23.453557