Author

Krinio Giannikou

Children's Hospital Los AngelesORCID 0000-0002-9633-3541Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:spatial transcriptomics· 2 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Aditya BagrodiaiD· 1 shared Andrew E. GoodspeediD· 1 shared Benjamin J. HuangiD· 1 shared Christopher KuoiD· 1 shared Deion Pena· 1 shared Diana J. LairdiD· 1 shared Ernesto J. RojasiD· 1 shared James F. AmatrudaiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Aditya BagrodiaORCID

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2 papers

Recent·Most cited

Integrated single-nuclei and spatial transcriptomic profiling of human sacrococcygeal teratomas reveals heterogeneity in cellular composition and X-chromosome inactivation

Ernesto J. Rojas, Krinio Giannikou, Benjamin J. Huang, Soo‐Jin Cho, Marco Cordero, Deion Pena, Lan Vu, Aditya Bagrodia, Sarkis Christopher Derderian, Tippi C. MacKenzie, Diana J. Laird

This study uses single-nuclei RNA-seq and spatial transcriptomics to analyze human sacrococcygeal teratomas, revealing cellular heterogeneity and X-chromosome inactivation patterns linked to sex bias.

bioRxiv · Jul 21, 2025 · PreprintCancer Biology

Tumor-associated stroma shapes the spatial tumor immune microenvironment of primary Ewing sarcomas

Christopher Kuo, Krinio Giannikou, N.-K. Wang, Mikako Warren, Andrew E. Goodspeed, Nick Shillingford, Masanori Hayashi, Micha Sam Brickman Raredon, James F. Amatruda

This study uses spatial transcriptomics to analyze Ewing sarcoma tumors, finding that localized tumors have more stromal enrichment and unique immune signals compared to metastatic tumors.

bioRxiv · Jan 31, 2025 · PreprintCancer Biology