Diana J. Laird

The paper presents a telomere-to-telomere genome assembly of the naked mole-rat and compares it with a related species to identify gene losses and duplications associated with unique traits.

This study identifies a brain-specific neuronal population critical for viable pregnancy by analyzing gene expression changes in estrogen receptor alpha-expressing neurons during gestation.

This study profiles mouse migratory primordial germ cells and their niches to show position-specific differences in non-canonical Wnt and Nodal-Lefty signaling during migration.

This study compares human and mouse ovarian biology across age using 3D-imaging, single-cell transcriptomics, and functional studies, identifying species-specific and age-related changes in follicle dynamics and gene expression.

This study identifies a mechanical defect in embryos from aged mothers that impairs implantation, showing increased trophectoderm contractility leads to defective spreading during implantation.

The paper investigates the cell and molecular origins of the primate ovarian reserve using rhesus macaques, identifying PG2 cells as the primary source of primordial follicles and describing the recruitment of fetal theca cells for hormone production.

This study uses single-nuclei RNA-seq and spatial transcriptomics to analyze human sacrococcygeal teratomas, revealing cellular heterogeneity and X-chromosome inactivation patterns linked to sex bias.

The paper shows that growing mouse oocytes receive mRNAs from granulosa cells, which are enriched for transcripts important for oocyte maturation and early embryo development.

The paper presents an updated reference genome for the naked mole-rat, identifying gene losses and gains linked to its unique physiological traits.

The paper shows that some oocytes from the first juvenile wave pause growth and later resume, contributing to fertility beyond puberty.

This study shows that male and female germ cells differ in their susceptibility to glucocorticoid signaling, with male germline cells being affected in RNA splicing while female cells are resistant.

The paper generates melanocytes from hPSCs through two distinct developmental trajectories and identifies T2-specific factors that promote melanoma metastasis.

This study shows that TET1's catalytic activity is essential for reprogramming imprinting control regions and sperm-specific hypomethylated regions during germline development.

This study uses 3D analysis to show radial meiotic initiation and intercellular bridges in human fetal ovaries, with variation in meiotic cell numbers and asynchronous transitions between mitotic and meiotic stages.

The paper shows that apoptosis in the fetal mouse testis removes developmentally defective germ cell clones based on intrinsic properties and epigenetic states.

The paper identifies heterogeneity in L1-ORF1p expression and its relationship with piRNA pathway activation and H3K9me3 levels in human fetal germ cells.