A tonic PDGFA-dependent niche organizer maintains alveolar homeostasis
Rebecca A. Shelley, Arvind Konkimalla, Thomas J. Whitlow, Kyoshiro Tsuge, Shuyu Liu, Michael T. Forrester, Aleksandra Tata, Purushothama Rao Tata
This study identifies PDGFA-expressing alveolar type 1 cells as a tonic niche organizer that maintains alveolar homeostasis by restraining fibroblast activation and promoting tissue repair.
bioRxiv · Oct 6, 2026 · PreprintCell Biology