Author

Thomas J. Whitlow

Duke UniversityORCID 0000-0002-7149-5835Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Organism:human· 2 Assay:scRNA-seq· 2 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Aleksandra TataiD· 3 shared Purushothama Rao TataiD· 3 shared Aditya PratapaiD· 1 shared Alan L SuiD· 1 shared Alejandro BarreraiD· 1 shared Alexias SafiiD· 1 shared Anthony J. RizzoiD· 1 shared Arvind KonkimallaiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCell Biology

Aleksandra TataORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A tonic PDGFA-dependent niche organizer maintains alveolar homeostasis

Rebecca A. Shelley, Arvind Konkimalla, Thomas J. Whitlow, Kyoshiro Tsuge, Shuyu Liu, Michael T. Forrester, Aleksandra Tata, Purushothama Rao Tata

This study identifies PDGFA-expressing alveolar type 1 cells as a tonic niche organizer that maintains alveolar homeostasis by restraining fibroblast activation and promoting tissue repair.

bioRxiv · Oct 6, 2026 · PreprintCell Biology

TP53-mediated bidirectional lineage plasticity drives alveolar epithelial cell extrusion and tissue remodeling

Jeremy M. Morowitz, Thomas J. Whitlow, Naoya Miyashita, Khaliun Enkhbayar, Aditya Pratapa, Rohit Singh, Aleksandra Tata, Purushothama Rao Tata

The paper identifies TP53 activation in alveolar epithelial cells as a driver of cell extrusion and tissue remodeling in IPF through bidirectional lineage plasticity.

bioRxiv · Jun 25, 2026 · PreprintCell Biology

Mechanosensitive genomic enhancers potentiate the cellular response to matrix stiffness

Brian D. Cosgrove, Lexi R. Bounds, Carson Key Taylor, Alan L Su, Anthony J. Rizzo, Alejandro Barrera, Tongyu Sun, Alexias Safi, Lingyun Song, Thomas J. Whitlow, Aleksandra Tata, Nahid Iglesias, Yarui Diao, Purushothama Rao Tata, Brenton D. Hoffman, , Charles A. Gersbach

The paper identifies mechanoenhancers that regulate transcription in response to matrix stiffness and shows their potential for reprogramming cellular responses to mechanical cues.

Science · Sep 25, 2025Peer-reviewedGenomics