Repeated exposure to viral and bacterial danger signals in Parkin deficient mice induces inflammation but fails to trigger parkinsonism
Amandine Even, Sriparna Mukherjee, Nicolas Giguère, Morgane Brouillard-Galipeau, Nathalia Luisa Oliveira, Priyabrata Halder, Claudie Beaulieu, Romain Cayrol, Nathalie Van Den Berge, Samantha Gruenheid, Louis‐Éric Trudeau
This study shows that repeated exposure to viral and bacterial danger signals in Parkin-deficient mice induces inflammation but does not cause dopaminergic denervation or motor dysfunction.
bioRxiv · Sep 28, 2026 · PreprintNeuroscience