Sriparna Mukherjee

This study shows that repeated exposure to viral and bacterial danger signals in Parkin-deficient mice induces inflammation but does not cause dopaminergic denervation or motor dysfunction.

This study shows that PINK1 in myeloid cells represses mtDNA release and immune signaling, which contributes to neuronal pathology in Parkinson's disease models.

This study identifies early immune dysregulation in PINK1 KO mice following intestinal infection, showing myeloid cell activation and T cell response as key factors in PD-like disease progression.

This study shows that a single Citrobacter rodentium infection increases blood-brain barrier permeability and triggers neuroinflammation in Pink1 knockout mice without dopamine neuron loss.

This study characterizes dopaminergic neurons in the gut using a DAT-cre reporter mouse line, revealing distinct subtypes with dual-transmitter content.

This study shows that mitochondrial antigen-specific CD8+ T cells can induce nigrostriatal dysfunction and dopamine neuron degeneration in mice, supporting an immune-driven mechanism in Parkinson's disease.

This study shows that phasic dopamine release in mice is not essential for basic motor behaviors, as motor functions remain intact despite near-complete loss of activity-dependent dopamine release.

This study shows that neurexins regulate dopamine neuron connectivity and neurotransmission by affecting dopamine reuptake and GABA co-release.

This study investigates the antiviral effects of atorvastatin against Chandipura and Japanese Encephalitis viruses, showing reduced viral replication and neuronal damage through hnRNPC-dependent mechanisms.

The paper identifies let-7a/b miRNAs in JEV-infected microglia and shows they promote neuronal damage via exosome-mediated caspase activation.