Author

Madison L. Lotstein

University of California, San FranciscoORCID 0000-0002-9653-4968Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:differential expression· 2 Organism:human· 2 Approach:benchmark study· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Gabriela K. FragiadakisiD· 2 shared Alexis J. CombesiD· 1 shared Ana Almonte-LoyaiD· 1 shared Aurora Rynda· 1 shared Brittany MoseriD· 1 shared Chioma J. MadubataiD· 1 shared Christina A. EkstrandiD· 1 shared Christopher BowmaniD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

Gabriela K. FragiadakisORCID

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2 papers

Recent·Most cited

Advancing CD38 from a marker of disease activity to an active regulator of interferon responses in juvenile dermatomyositis

Brittany Moser, Chioma J. Madubata, Marissa Y. Chou, Madison L. Lotstein, Zilan Zheng, Tushar Agashe, Ana Almonte-Loya, Taylor N. LaFlam, Aurora Rynda, Jennifer P. Fox, Jessica L. Turnier, Johann Gudjonsson, Joanne Michelle Kahlenberg, Gabriela K. Fragiadakis, Kanneboyina Nagaraju, , Jessica A Neely

This study identifies CD38 as a regulator of interferon responses in juvenile dermatomyositis and suggests its inhibition as a potential therapeutic strategy.

bioRxiv · Oct 20, 2026 · PreprintImmunology

Single-cell spatial transcriptomics of fixed, paraffin-embedded biopsies reveals colitis-associated cell networks

Elvira Mennillo, Madison L. Lotstein, Gyehyun Lee, Julian H. Hou, Vrinda Johri, Donna Leet, Christina A. Ekstrand, Jessica Tsui, Jun He, Uma Mahadevan, Walter L. Eckalbar, Ryan M. Gill, Christopher Bowman, David Yoonsuk Oh, Gabriela K. Fragiadakis, , Alexis J. Combes

This study develops an iSCST framework for FFPE biopsies, identifying colitis-associated cell networks and VDZ response signatures in IBD patients.

Journal of Clinical Investigation · Jun 9, 2026Peer-reviewedImmunology