Author

Alexandre Grassart

Centre National de la Recherche ScientifiqueORCID 0000-0002-9656-4331Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:organoid / primary culture· 2 Research Focus:cell type annotation· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Aurélie Burette· 3 shared Nathalie DeboosèreiD· 3 shared Elisabeth WerkmeisteriD· 2 shared Elise DelannoyiD· 2 shared Priscille M BrodiniD· 2 shared Roxane SiméoneiD· 2 shared Sophie Salomé‐DesnouleziD· 2 shared Yoel DaganiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersMicrobiology

Aurélie Burette

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Galectin-3 recruitment at the Mycobacterium tuberculosis-containing phagosome is critical in macrophage but dispensable in epithelial cells

Yoel Dagan, Nathalie Deboosère, Eugenie Boulagnon, Aurélie Burette, Arnaud Machelart, Olivier Molendi‐Coste, Sophie Salomé‐Desnoulez, Elisabeth Werkmeister, Roxane Siméone, Alexandre Grassart, Priscille M Brodin

This study shows that Galectin-3 recruitment to Mtb-containing vacuoles is essential in macrophages but not in epithelial cells, highlighting its role in restricting bacterial growth.

bioRxiv · Jun 5, 2026 · PreprintMicrobiology

Development of a cost-effective Alveolus-on-Chip for studying Mycobacterium tuberculosis infection.

Nathalie Deboosère, Yoel Dagan, Aurélie Burette, Elise Delannoy, Sophie Salomé‐Desnoulez, Elisabeth Werkmeister, Roxane Siméone, Priscille M Brodin, Alexandre Grassart

The paper develops a cost-effective alveolus-on-chip to study early Mycobacterium tuberculosis infection, showing macrophages enhance infection susceptibility.

bioRxiv · Apr 30, 2026 · PreprintMicrobiology

Gut-on-Chip Methodology Based on 3D-Printed Molds: A Cost-Effective and Accessible Approach

Elise Delannoy, Aurélie Burette, Sébastien Janel, Sabine Poiret, Nathalie Deboosère, Catherine Daniel, Alexandre Grassart

This paper presents a low-cost, open-access 3D-printed Gut-on-Chip method for gut research, demonstrating its functionality with Caco-2 cells.

Lab on a Chip · Jan 1, 2025Peer-reviewedBioengineering