Roxane Siméone

This study shows that Galectin-3 recruitment to Mtb-containing vacuoles is essential in macrophages but not in epithelial cells, highlighting its role in restricting bacterial growth.

The paper develops a cost-effective alveolus-on-chip to study early Mycobacterium tuberculosis infection, showing macrophages enhance infection susceptibility.

This study uses human airway organoids to model tuberculosis infection, showing mycobacteria infect epithelial cells with low efficiency and the organoid microenvironment controls but does not eliminate the pathogen.