Major Metabolites From Hypericum perforatum L., Hyperforin And Hypericin, Are Both Active Against Human Coronaviruses
Imelda Raczkiewicz, Céline Rivière, Peggy Bouquet, Lowiese M. B. Desmarets, Audrey Tarricone, Charline Camuzet, Nadine François, Guillaume Lefèvre, Jennifer Samaillie, F. Silva Angulo, Cyril Robil, François Trottein, Sevser Şahpaz, J. D. Dubuisson, Sandrine Belouzard, , Karin Séron
This study shows that hyperforin from Hypericum perforatum inhibits multiple coronaviruses, including SARS-CoV-2, with antiviral activity confirmed in human cells and potential for combination therapy with remdesivir.
bioRxiv · Apr 9, 2024 · PreprintMicrobiology