Crystal structures of forty- and seventy-one-substitution variants of hydroxynitrile lyase from rubber tree
Colin T. Pierce, Panhavuth Tan, Lauren R. Greenberg, Meghan E. Walsh, Ke Shi, Alana H. Nguyen, Elyssa L. Meixner, Sharad Sarak, Hideki Aihara, Robert L. Evans, Romas J. Kazlauskas
The paper describes the creation and structural analysis of HbHNL variants with 40 and 71 mutations to resemble SABP2, showing increased structural similarity to SABP2 with more mutations.
bioRxiv · Mar 30, 2025 · PreprintBiochemistry