Aging impairs astrocytes in the human cerebral cortex
Alexander Popov, Nadezda A. Brazhe, Kseniia I. Morozova, Яшин Константин Сергеевич, Maxim L. Bychkov, Olga Nosova, Oksana I. Sutyagina, Alexey Brazhe, E. Yu. Parshina, Li Li, Igor Aleksandrovich Medyanik, Dmitriy E. Korzhevsky, Zakhar O. Shenkarev, Ekaterina N. Lyukmanova, Alexei Verkhratsky, Alexey V. Semyanov
This study shows that aging impairs astrocyte morphology and mitochondrial function in the human cerebral cortex, while neurons remain unaffected.
bioRxiv · Oct 31, 2022 · PreprintNeuroscience