Alexey Brazhe

The paper examines population calcium responses in cortical astrocytes during locomotion, identifying four phases and a temporal threshold of ~5 seconds for superevent formation.

This paper introduces a framework to generate branching morphologies using fast-marching algorithms with feedback mechanisms, demonstrating its ability to create realistic 2D and 3D structures.

The paper investigates how GABAergic inputs influence dendritic integration through spatiotemporal differences in polarization and shunting in rat hippocampal neurons.

This study examines how cerebral blood flow and metabolic responses of astrocytes and neurons change during locomotion, revealing distinct mitochondrial behaviors and potential signaling roles of astrocytes.

This study shows that aging impairs astrocyte morphology and mitochondrial function in the human cerebral cortex, while neurons remain unaffected.

The paper shows astrocytes produce nitric oxide from nitrite via mitochondrial sulfite oxidase during hypoxia, modulating cerebral blood flow.

A high-fat diet increases astrocytic lipid content and branching, enhancing glutamate clearance and exploratory behavior in young mice.

The paper develops a model of astrocyte networks that incorporates realistic morphology and dynamics to simulate Ca2+ transients and wave propagation.

This study shows that aging reduces astrocytic processes and function, which correlates with impaired synaptic plasticity in the hippocampus.

The paper shows circadian rhythms in hippocampal CA1 neurons and astrocytes affect synaptic plasticity through changes in NMDA receptor expression and astrocytic proximity to synapses, altering glutamate clearance and cognitive processing.

This study shows that somatosensory stimulation evokes astrocytic calcium signaling in the ischemic penumbra, with preserved responses in aged mice, suggesting astrocytic activity may contribute to neuroprotection after stroke.

This study shows that caloric restriction in mice alters astrocytic morphology and Ca2+ activity, enhancing synaptic plasticity and LTP in hippocampal synapses.