Author

Christian A. DeJarnette

University of Tennessee Health Science CenterORCID 0000-0002-9733-9152Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Research Focus:host-pathogen & immune response· 2 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Glen E. PalmeriD· 2 shared Anang A. ShelatiD· 1 shared Justin B. GregoriD· 1 shared Katie M. Tucker· 1 shared Nathaniel R. TwarogiD· 1 shared Parker Reitler· 1 shared Ravinder Kumar· 1 shared Ravinder KumariD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 24 mutual co-author links

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2 shared papersMicrobiology

Glen E. PalmerORCID

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2 papers

Recent·Most cited

Loss of the high-affinity vacuolar Ca2+ pump Pmc1p confers echinocandin tolerance in Candida albicans through enhancing calcineurin-based responses.

Justin B. Gregor, Ravinder Kumar, Christian A. DeJarnette, Glen E. Palmer

This study shows that loss of Pmc1p in Candida albicans increases tolerance to echinocandins by enhancing calcineurin signaling.

bioRxiv · Aug 28, 2026 · PreprintMicrobiology

A screen to identify antifungal antagonists reveals a variety of pharmacotherapies induce echinocandin tolerance in Candida albicans.

Parker Reitler, Christian A. DeJarnette, Ravinder Kumar, Katie M. Tucker, Tracy L. Peters, Nathaniel R. Twarog, Anang A. Shelat, Glen E. Palmer

This study identifies over 20 drugs that induce echinocandin tolerance in Candida albicans, revealing their mechanism involves multiple signaling pathways and transcriptional changes.

Antimicrobial Agents and Chemotherapy · Aug 18, 2025Peer-reviewedMicrobiology