Loss of Kallmann syndrome-associated gene WDR11 disrupts primordial germ cell development by affecting canonical and non-canonical Hedgehog signalling
Ji‐Young Lee, Yeon-Joo Kim, Paris Ataliotis, Hyung‐Goo Kim, Dae‐Won Kim, Dorothy C. Bennett, Nigel Andrew Brown, Lawrence Clarke Layman, Soo‐Hyun Kim
This study shows that WDR11 loss disrupts primordial germ cell development by impairing both canonical and non-canonical Hedgehog signaling pathways.
bioRxiv · Sep 6, 2020 · PreprintGenetics