Timothy J. Mohun

The paper quantitatively and morphologically analyzes the development of ventricular walls in mouse and human hearts, finding that slow trabecular layer growth, not compaction, drives morphological changes.

This study identifies a mutation in SMCHD1 that enhances gene silencing and disrupts developmental processes, revealing distinct roles of SMCHD1 in chromatin structure and gene regulation.

This study identifies maternal iron deficiency as an environmental teratogen causing congenital heart disease in mice, with potential implications for human health.

This study shows that knocking out Adprhl1 in Xenopus leads to heart chamber growth defects and myofibril assembly failure, revealing a critical role for a non-catalytic substrate binding site in cardiac development.

The paper shows Pax9 is essential for cardiovascular development and interacts with Tbx1 in the pharyngeal endoderm to regulate 4th pharyngeal arch artery formation.

This study identifies WDR11 as a regulator of Hedgehog signaling and ciliogenesis, linking its mutations to ciliopathy and Kallmann syndrome.