CD8+ T-cells protect against experimental atherosclerosis through antigen specific interactions in the plaque
Eveline A de Vlieger, Maaike J.M. de Jong, Jeroen Molenaar, Pier P Lindenbergh, Kun Liu, Rosemarijn M.H. Hamelynck, Amanda C Foks, Ilze Bot, B. A. J. A. van de Sluis, Bram Sluetter
This study shows that antigen-specific CD8+ T cells reduce atherosclerotic plaque burden and stabilize plaques by decreasing secondary necrosis and CD47 expression on foam cells.
bioRxiv · Nov 10, 2026 · PreprintPathology