Bart van de Sluis

This study shows that antigen-specific CD8+ T cells reduce atherosclerotic plaque burden and stabilize plaques by decreasing secondary necrosis and CD47 expression on foam cells.

This study identifies COPI coatomer subunits that regulate LDL receptor activity, apoB secretion, and hepatic lipid storage, with genetic variants linked to elevated LDL-C levels.

This study shows that hepatic VPS35 deficiency disrupts lysosomal cholesterol metabolism, leading to increased cholesterol levels in plasma and liver.

This study shows that SERF2 deletion changes amyloid fibril structure in Alzheimer's mouse models, suggesting SERF's role in modifying amyloid aggregation.