Bram Slütter

This study shows that antigen-specific CD8+ T cells reduce atherosclerotic plaque burden and stabilize plaques by decreasing secondary necrosis and CD47 expression on foam cells.

This study shows that stereochemical identity of lipid nanoparticles affects their physicochemical properties and protein expression through internal lipid organization.

The paper identifies a single-nucleotide change in the Kozak sequence that consistently enhances protein expression across different UTR contexts and coding sequences.

The paper shows that conjugated PRR ligands enhance immune activation, act as adjuvants, and induce antitumor responses in a mouse model.