Restoration of mitochondrial function to metabolically stressed astrocytes by fusion with mesenchymal stromal cells.
Remy T. Schneider, Matthew R. Rowe, Rebecca Smullin Dawson, Kateřina Komrsková, Jiřı́ Neužil, Michael V. Berridge, Patries M. Herst, Melanie Jane McConnell
This study shows that stressed astrocytes can restore mitochondrial function through fusion with mesenchymal stromal cells, as evidenced by mitochondrial DNA transfer and long-term functional recovery.
bioRxiv · Feb 3, 2025 · PreprintCell Biology