Polygenic Prediction of Substance Use Disorders in Clinical and Population Samples
Peter B. Barr, Albert J. Ksinan, Jinni Su, Emma C. Johnson, Jacquelyn Leigh Meyers, Leah Flury Wetherill, Antti Latvala, Fazil Alıev, Grace Chan, Samuel Kuperman C, John I. Nürnberger, Chella Kamarajan, Andrey P. Anokhin, Arpana Agrawal A, Richard J. Rose, , Danielle M. Dick
This study uses polygenic risk scores to predict substance use disorders in two samples, finding increased risk with higher scores but limited clinical utility.
bioRxiv · Aug 30, 2019 · PreprintGenetics